Eukaryotic cell biology is temporally coordinated to support the energetic demands of protein homeostasis


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Eukaryotic cell biology is temporally coordinated to support the energetic demands of protein homeostasis

Yeast physiology is temporally regulated, this becomes apparent under nutrient-limited conditions and results in respiratory oscillations (YROs). YROs share features with circadian rhythms and interact with, but are independent of, the cell division cycle. Here, we show that YROs minimise energy expenditure by restricting protein synthesis until sufficient resources are stored, while maintaining osmotic homeostasis and protein quality control.

Although nutrient supply is constant, cells sequester and store metabolic resources via increased transport, autophagy and biomolecular condensation. Replete stores trigger increased H+ export which stimulates TORC1 and liberates proteasomes, ribosomes, chaperones and metabolic enzymes from non-membrane bound compartments. This facilitates translational bursting, liquidation of storage carbohydrates, increased ATP turnover, and the export of osmolytes.

We propose that dynamic regulation of ion transport and metabolic plasticity are required to maintain osmotic and protein homeostasis during remodelling of eukaryotic proteomes, and that bioenergetic constraints selected for temporal organisation that promotes oscillatory behaviour.

Recent advances in synthetic biology-enabled and natural whole-cell optical biosensing of heavy metals

A large number of scientific works have been published on whole-cell heavy metal biosensing based on optical transduction. The advances in the application of biotechnological tools not only have continuously improved the sensitivity, selectivity, and detection range for biosensors but also have simultaneously unveiled new challenges and restrictions for further improvements.

This review highlights selected aspects of whole-cell biosensing of heavy metals using optical transducers. We have focused on the progress in genetic modulation in regulatory and reporter modules of recombinant plasmids that has enabled improvement of biosensor performance.

Simultaneously, an attempt has been made to present newer platforms such as microfluidics that have generated promising results and might give a new turn to the optical biosensing field.

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Cotinine-BSA Conjugate

COTN15-BSA 0.5 mg
EUR 286

Positive control tissue section for each antibody; Based on availability INQUIRE

Control-Slides Set of 5
EUR 176

BSA Control for AGE-BSA

35R-AA007 10 mg
EUR 224
Description: BSA Control for AGE protein (BSA modified), Cat No. 30R-AA007

CEL-BSA Control

STA-302 100 µg
EUR 322
Description:
  • N-epsilon-(carboxyethyl) lysine (CEL) modified BSA may be used as a positive control. 100 µg at 1 mg/mL in PBS.
  • Provided at 1 mg/mL in 1X PBS

MG-BSA Control

STA-306 100 µg
EUR 322
Description:
  • Methylglyoxal-BSA (MG-BSA) may be used as a positive control. 100 µg at 1 mg/mL in PBS.
  • Provided at 1 mg/mL

CML-BSA Control

STA-314 100 µg
EUR 322
Description:
  • CML-BSA may be used as a positive control. 100 µg.
  • Provided at 1 mg/mL in 1X PBS

MDA-BSA Control

STA-333 100 µg
EUR 322
Description:
  • MDA-BSA (Malondialdehyde-BSA) may be used as a positive control. 100 µg.
  • Provided at 1 mg/mL in 1X PBS

Bovine Serum Albumin Biotinylated (Biotin-BSA)

BTN-BSA 5 mg
EUR 286

Ibrutinib drug-Bovine Serum Albumin (BSA) Conjugate

IBT15-BSA 100 ug
EUR 529

Phosphoserine-BSA control protein

PSER15-N 100 ug
EUR 164

Dinitrophenyl (DNP)-BSA protein Conjugate

AV-9330-BSA 10 mg
EUR 286

mPEG-BSA (Molecular Weight: 5,000-linear)

PEG-BSA-05K 100 ug
EUR 286

mPEG-BSA (Molecular Weight: 10,000-linear)

PEG-BSA-10K 100 ug
EUR 286

mPEG-BSA (Molecular Weight: 20,000-linear)

PEG-BSA-20K 100 ug
EUR 286

mPEG-BSA (Molecular Weight: 40,000-linear)

PEG-BSA-40K 100 ug
EUR 286

HNE antibody

20R-HG007 100 ug
EUR 300
Description: Goat polyclonal HNE antibody

4-Hydroxynonenal (HNE)-BSA protein conjugate for ELISA (in PBS)

HNE15-R 100 ug
EUR 347

(DRAAGQPAG)3 peptide (repeat-sequence peptide of the P. vivax circumsporozoite protein, CSP) conjugated with BSA

DRAA31-BSA 0.5 mg
EUR 529

(PPPPNAND)3 peptide (repeat-sequence peptide of the P. berghei circumsporozoite protein, CSP) conjugated with BSA

PPPP321-BSA 0.5 mg
EUR 529

(NVDP)4 peptide (minor repeat-sequence peptide of the P. falciparum circumsporozoite protein, CSP) conjugated with BSA

NVDP41-BSA 0.5 mg
EUR 529

(NANP)5 peptide (25-aa, repeat-sequence peptide of the P. falciparum circumsporozoite protein, CSP) conjugated with BSA

NANP51-BSA 0.5 mg
EUR 529

Protein Tyrosine Nitration Control (Nitrotyrosine-BSA)

STA-304 10 ?g
EUR 241
Description:
  • Protein Tyrosine Nitration Control (Nitrotyrosine-BSA) may be used as a positive control. 10 µg.
  • Provided at 0.1 mg/mL

Oxidized Protein Immunoblot Control (Carbonyl-BSA)

STA-309 10 ?g
EUR 241
Description:
  • Oxidized Protein Immunoblot Control (Carbonyl-BSA) may be used as a positive control. 10 µg.
  • Provided at 50 µg/mL

Bovine Serum Albumin (BSA) ELISA Kit

DLR-BSA-Ge-48T 48T
EUR 387
Description: A competitive inhibition quantitative ELISA assay kit for detection of Bovine Serum Albumin (BSA) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Bovine Serum Albumin (BSA) ELISA Kit

DLR-BSA-Ge-96T 96T
EUR 494
Description: A competitive inhibition quantitative ELISA assay kit for detection of Bovine Serum Albumin (BSA) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Bovine Serum Albumin (BSA) modified with 4-Hydroxy nonenal (4-HNE)

SPR-211A 0.05 mg
EUR 256
Description: Untagged synthetic panspecies 4-Hydroxynonenal BSA Conjugate for WB, ELISA. The biological activity of this protein has not yet been tested.

Bovine Serum Albumin (BSA) modified with 4-Hydroxy nonenal (4-HNE)

SPR-211B 2x0.05 mg
EUR 370
Description: Untagged synthetic panspecies 4-Hydroxynonenal BSA Conjugate for WB, ELISA. The biological activity of this protein has not yet been tested.

Bovine Serum Albumin (BSA) modified with 4-Hydroxy nonenal (4-HNE)

SPR-211C 4x0.05 mg
EUR 523
Description: Untagged synthetic panspecies 4-Hydroxynonenal BSA Conjugate for WB, ELISA. The biological activity of this protein has not yet been tested.

Bovine serum albumin (BSA) removal kit (Antibody based aff matrix; sufficient to remove 1-2 mg BSA from Bioprocessed material), 2 ml aff column

800-302-BSA 1 Kit
EUR 347

Bovine serum albumin (BSA) removal kit (Antibody based aff matrix; sufficient to remove 10-20 mg BSA from Bioprocessed material), 10 ml aff column

800-310-BSA 1 Kit
EUR 895

Bovine serum albumin (BSA) removal kit (Antibody based aff matrix; sufficient to remove 25-50 mg BSA from Bioprocessed material), 25 ml aff column

800-325-BSA 1 Kit
EUR 1450

General Bovine Serum Albumin (BSA) ELISA Kit

RD-BSA-Ge-48Tests 48 Tests
EUR 527

General Bovine Serum Albumin (BSA) ELISA Kit

RD-BSA-Ge-96Tests 96 Tests
EUR 732

General Bovine Serum Albumin (BSA) ELISA Kit

RDR-BSA-Ge-48Tests 48 Tests
EUR 551

General Bovine Serum Albumin (BSA) ELISA Kit

RDR-BSA-Ge-96Tests 96 Tests
EUR 766

Monoclonal Anti-4 HNE (4-HNE; 4-hydroxynonenal) IgG

HNE13-M 100 ul
EUR 482

4-Hydroxynonenal (HNE)-BSA protein conjugate for Western blots (in sample buffer)

HNE11-C 100 ul
EUR 286

4-Hydroxynonenal (HNE)-BSA protein conjugate for Western blots (in sample buffer)

HNE12-C 100 ul
EUR 286

Vaccigel Alum adjuvant adsorbed with Bovine Serum Albumin (BSA @1 mg/ml), Vaccine adjuvant

AV-1010-BSA 1 ml
EUR 286

Pre-diluted BSA (bovine serum albumin) standards (1 set) for BCA Optima Protein Assay kit

BCA-BSA-1 1 pk
EUR 164

Pre-diluted BSA (bovine serum albumin) standards (750 ug/ml) for BCA Optima Protein Assay kit

BCA-BSA-750 1 ml
EUR 225

BSA and BGG Stock standards (1 vial each @ 2 mg/ml) for BCA Optima Protein Assay kit

BSA-BGG-1 1 pk
EUR 286

Sheep 4-HNE ELISA Kit

ESH0210 96Tests
EUR 521

Mouse 4-HNE ELISA Kit

EMH0210 96Tests
EUR 521

Monkey 4-HNE ELISA Kit

EMKH0210 96Tests
EUR 521

Porcine 4-HNE ELISA Kit

EPH0210 96Tests
EUR 521

Rat 4-HNE ELISA Kit

ERH0210 96Tests
EUR 521

Rabbit 4-HNE ELISA Kit

ERTH0210 96Tests
EUR 521

Goat 4-HNE ELISA Kit

EGTH0210 96Tests
EUR 521

Canine 4-HNE ELISA Kit

ECH0210 96Tests
EUR 521

Chicken 4-HNE ELISA Kit

ECKH0210 96Tests
EUR 521

Human 4-HNE ELISA Kit

EHH0210 96Tests
EUR 521

Bovine 4-HNE ELISA Kit

EBH0210 96Tests
EUR 521

4-Hydroxynonenal (4-HNE) Antibody

abx411903-01ml 0.1 ml
EUR 509

Polyclonal HNE / Neutrophil Elastase Antibody

APS00008G 0.05mg
EUR 484
Description: A polyclonal antibody raised in Sheep that recognizes and binds to Human HNE / Neutrophil Elastase . This antibody is tested and proven to work in the following applications:

4 hydroxynonenal (HNE), >98% pure

HNE51-1 1 mg
EUR 202

4 hydroxynonenal (HNE), >98% pure

HNE51-5 5 mg
EUR 651

anti-4-HNE (HNEJ-2)

LF-MA90010 20 ug
EUR 360
Description: Mouse monoclonal to 4-HNE

anti-4-HNE (HNEJ-2)

LF-MA90011 100 ug
EUR 891
Description: Mouse monoclonal to 4-HNE

4-HNE ELISA KIT|Human

EF006163 96 Tests
EUR 689

Malondialdehyde (MDA)-BSA Conjugate positive control for Western/ELISA

MDA35-N-100 100 ug
EUR 286

Pre-diluted BSA (bovine serum albumin) standards (250, 125, 62.5, 31.25, and 0.0 ug/ml) for BCA Optima Protein Assay kit

BCA-BSA-2 1 pk
EUR 164

Albumin (Human, Mouse, rat, bovine and others) removal kit (synthetic dye based matrix; sufficient to remove 20-40 mg BSA from Bioprocessed material), 2 ml aff column

800-200-BSA 1 kit
EUR 286

Albumin (Human, Mouse, rat, bovine and others) removal kit (synthetic dye based matrix; sufficient to remove 50-100 mg BSA from Bioprocessed material), 5 ml aff column

800-205-BSA 1 kit
EUR 773

Albumin (Human, Mouse, rat, bovine and others) removal kit (synthetic dye based matrix; sufficient to remove 250-500 mg BSA from Bioprocessed material), 25 ml aff column

800-225-BSA 1 kit
EUR 2425

Guinea Pig 4-HNE ELISA Kit

EGH0210 96Tests
EUR 521

4-Hydroxynonenal (4-HNE) ELISA Kit

abx257639-96tests 96 tests
EUR 668

OxiSelect HNE Adduct Competitive ELISA Kit

STA-838 96 assays
EUR 798
Description: 4-hydroxynonenal (4-HNE or HNE) is a well known by-product of lipid peroxidation and is widely accepted as a stable marker for oxidative stress. Our OxiSelect HNE Adduct Competitive ELISA Kit measures the formation of HNE adducts to any protein residue using a competitive ELISA format.

OxiSelect HNE Adduct Competitive ELISA Kit

STA-838-5 5 x 96 assays
EUR 3240
Description: 4-hydroxynonenal (4-HNE or HNE) is a well known by-product of lipid peroxidation and is widely accepted as a stable marker for oxidative stress. Our OxiSelect HNE Adduct Competitive ELISA Kit measures the formation of HNE adducts to any protein residue using a competitive ELISA format.

Rat 4-Hydroxynonenal(HNE)ELISA Kit

CSB-EQ027232RA-24T 1 plate of 24 wells
EUR 165
Description: Quantitativecompetitive ELISA kit for measuring Rat 4-Hydroxynonenal (HNE) in samples from serum, plasma. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rat 4-Hydroxynonenal(HNE)ELISA Kit

1-CSB-EQ027232RA
  • EUR 900.00
  • EUR 5476.00
  • EUR 2900.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativecompetitive ELISA kit for measuring Rat 4-Hydroxynonenal(HNE) in samples from serum, plasma. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse 4-Hydroxynonenal (HNE)ELISA Kit

CSB-E13412m-24T 1 plate of 24 wells
EUR 165
Description: Quantitativesandwich ELISA kit for measuring Mouse 4-Hydroxynonenal (HNE) in samples from serum, plasma. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse 4-Hydroxynonenal (HNE)ELISA Kit

1-CSB-E13412m
  • EUR 900.00
  • EUR 5476.00
  • EUR 2900.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Mouse 4-Hydroxynonenal (HNE) in samples from serum, plasma. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human 4-Hydroxynonenal (HNE)ELISA Kit

CSB-E16214h-24T 1 plate of 24 wells
EUR 165
Description: Quantitativecompetitive ELISA kit for measuring Human 4-Hydroxynonenal (HNE) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human 4-Hydroxynonenal (HNE)ELISA Kit

1-CSB-E16214h
  • EUR 804.00
  • EUR 5099.00
  • EUR 2704.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativecompetitive ELISA kit for measuring Human 4-Hydroxynonenal (HNE) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rabbit Anti-4 hydroxynonenal (HNE) antiserum

HNE11-S 100 ul
EUR 457

4-Hydroxynonenal (4-HNE) ELISA Kit

E4645-100
EUR 865

ELISA kit for 4-HNE (4-Hydroxynonenal)

E-EL-0128 1 plate of 96 wells
EUR 377
Description: A competitive ELISA kit for quantitative measurement of 4-HNE (4-Hydroxynonenal) in samples from Serum, Plasma, Cell supernatant

Mouse 4-Hydroxynonenal (4-HNE) ELISA Kit

abx257660-96tests 96 tests
EUR 754

Human 4-Hydroxynonenal (4-HNE) ELISA Kit

abx251411-96tests 96 tests
EUR 754

Goat Anti-4-Hydroxynonenal (HNE) Polyclonal Antibody

STA-034 100 µg
EUR 664
Description: Goat Anti-4-hydroxynonenal Polyclonal Antibody is Affinity purified and suitable for Western blot or ELISA. Suitable for use with any species. 100 µg.

Rabbit Anti-4-Hydroxynonenal (HNE) Polyclonal Antibody

STA-035 100 µg
EUR 664
Description: Rabbit Anti-4-hydroxynonenal Polyclonal Antibody is Affinity purified and suitable for Western blot or ELISA. Suitable for use with any species. 100 µg.

Mouse 4-HNE(4-Hydroxynonenal) ELISA Kit

EM1583 96T
EUR 524.1
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Mus ;Sensitivity: 18.75pg/ml

Rat 4-HNE(4-Hydroxynonenal) ELISA Kit

ER1587 96T
EUR 524.1
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Rattus;Sensitivity: 18.75 pg/ml

Human 4-HNE(4-Hydroxynonenal) ELISA Kit

EH2080 96T
EUR 524.1
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75 pg/ml

Goat Anti-4 hydroxynonenal (HNE) antiserum #2

HNE12-S 100 ul
EUR 457

BSA

31C-CH0114 50 mg
EUR 133
Description: Bovine Serum Albumin for use in the research laboratory

Testosterone 3 BSA Protein (BSA)

abx060856-1mg 1 mg
EUR 578

Ibrutinib drug-Human Serum Albumin Conjugate

IBT16-BSA 100 ug
EUR 529

OxiSelect HNE Adduct Competitive ELISA Kit, Trial Size

STA-838-T 32 assays
EUR 421
Description: 4-hydroxynonenal (4-HNE or HNE) is a well known by-product of lipid peroxidation and is widely accepted as a stable marker for oxidative stress. Our OxiSelect HNE Adduct Competitive ELISA Kit measures the formation of HNE adducts to any protein residue using a competitive ELISA format.

Mouse (mrl/lpr) serum containing autoantibodies to HNE

HNE31-M 100 ul
EUR 482

Control siRNA Vector (pGB-control)

9500C-20
EUR 338

Histamine [G-BSA] (G-G-BSA)

DAG3327 1mg
EUR 1234

Cyclic citrullinated peptide-BSA(CCP-BSA)

E64I00802 100ug
EUR 343

BSA Antigen

IM112 1 ml
EUR 285
Description: BSA Antigen by Cygnus Technologies is available in Europe via Gentaur.

Paromomycin [BSA]

DAG-P2529 1mg
EUR 780

Ciclosporin [BSA]

DAG-WZ017A 1 mg
EUR 1040

Acetaminophen [BSA]

DAG2957 0.5mg
EUR 780

Immune evasion in renal cell carcinoma: biology, clinical translation, future directions

Targeted therapies and immune checkpoint inhibitors have advanced the treatment landscape of Renal Cell Carcinoma (RCC) over the last decade. While checkpoint inhibitors have demonstrated survival benefit and are currently approved in the front-line and second-line settings, primary and secondary resistance is common.

A comprehensive understanding of the mechanisms of immune evasion in RCC is therefore critical to the development of effective combination treatment strategies. This article reviews the current understanding of the different, yet coordinated, mechanisms adopted by RCC cells to evade immune killing; summarizes various aspects of clinical translation thus far, including the currently registered RCC clinical trials exploring agents in combination with checkpoint inhibitors; and provides perspectives on the current landscape and future directions for the field.

Dysregulation of club cell biology in idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a progressive, chronic fibrotic lung disease with an irreversible decline of lung function. “Bronchiolization”, characterized by ectopic appearance of airway epithelial cells in the alveolar regions, is one of the characteristic features in the IPF lung.

Based on the knowledge that club cells are the major epithelial secretory cells in human small airways, and their major secretory product uteroglobin (SCGB1A1) is significantly increased in both serum and epithelial lining fluid of IPF lung, we hypothesize that human airway club cells contribute to the pathogenesis of IPF.

By assessing the transcriptomes of the single cells from human lung of control donors and IPF patients, we identified two SCGB1A1+ club cell subpopulations, highly expressing MUC5B, a significant genetic risk factor strongly associated with IPF, and SCGB3A2, a marker heterogeneously expressed in the club cells, respectively. Interestingly, the cellular proportion of SCGB1A1+MUC5B+ club cells was significantly increased in IPF patients, and this club cell subpopulation highly expressed genes related to mucous production and immune cell chemotaxis.

In contrast, though the cellular proportion did not change, the molecular phenotype of the SCGB1A1+SCGB3A2high club cell subpopulation was significantly altered in IPF lung, with increased expression of mucins, cytokine and extracellular matrix genes. The single cell transcriptomic analysis reveals the cellular and molecular heterogeneity of club cells, and provide novel insights into the biological functions of club cells in the pathogenesis of IPF.

Variations in drug sensitivity between two-dimensional and three-dimensional tradition methods in triple-negative breast most cancers cell strains

 

Three-dimensional (3D) tradition displays tumor biology complexities in contrast with two-dimensional (2D) tradition. Thus, 3D tradition has attracted consideration in cell biology research together with drug sensitivity exams.

 

Herein, we investigated variations in anticancer drug sensitivities between 2D and 3D tradition methods in triple-negative breast most cancers (TNBC) cell strains. 13 TNBC cell strains have been maintained in 2D and 3D cultures for Three days earlier than drug publicity. Cell morphology within the 3D tradition was examined by phase-contrast microscopy.

 

Sensitivities to epirubicin (EPI), cisplatin (CDDP), and docetaxel (DTX) have been investigated by cell viability assay in each cultures and in contrast. The IC50s of all Three medication have been considerably greater within the 3D tradition than within the 2D tradition in most cell strains.

 

These have been correlated between the 2D and 3D cultures in EPI (R = 0.555) and CDDP (R = 0.955), however not in DTX (R = 0.221). Spherical spheroid-forming cells have been extra proof against brokers than grape-like sorts. In conclusion, 3D tradition was extra proof against all Three medication than 2D tradition in most TNBC cell strains. Sensitivity to CDDP was extremely correlated between the 2D and 3D cultures, however to not DTX. 2D tradition could also be acceptable for sensitivity take a look at for DNA-damaging brokers.

 

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pAAV-RC1 Vector

VPK-421 10 µg
EUR 647
Description: The pAAV-RC1 vector contains the rep and cap genes required to generated recombinant AAV of serotype 1. Co-transfect with other packaging plasmids and an expression vector into 293 cells for AAV-1 packaging.

pAAV-RC3 Vector

VPK-423 10 µg
EUR 647
Description: The pAAV-RC3 vector contains the rep and cap genes required to generated recombinant AAV of serotype 3. Co-transfect with other packaging plasmids and an expression vector into 293 cells for AAV-3 packaging.

pAAV-RC4 Vector

VPK-424 10 µg
EUR 647
Description: The pAAV-RC4 vector contains the rep and cap genes required to generated recombinant AAV of serotype 4. Co-transfect with other packaging plasmids and an expression vector into 293 cells for AAV-4 packaging.

pAAV-RC5 Vector

VPK-425 10 µg
EUR 647
Description: The pAAV-RC5 vector contains the rep and cap genes required to generated recombinant AAV of serotype 5. Co-transfect with other packaging plasmids and an expression vector into 293 cells for AAV-5 packaging.

pAAV-RC6 Vector

VPK-426 10 µg
EUR 647
Description: The pAAV-RC6 vector contains the rep and cap genes required to generated recombinant AAV of serotype 6. Co-transfect with other packaging plasmids and an expression vector into 293 cells for AAV-6 packaging.

pAAV-RC9 vector

PVT12073 2 ug
EUR 524

pAAV-DJ vector

PVT12151 2 ug
EUR 438

pAAV-RC6

PVT14647 2 ug
EUR 703

pAAV- RC

PVT2103 2 ug
EUR 241

pAAV-GFP Control Vector

AAV-400 10 µg
EUR 566
Description: Use this control vector to co-transfect along with AAV packaging vectors to produce a recombinant AAV control.

pAAV-Cre Control Vector

AAV-401 10 µg
EUR 566
Description: Use this control vector to co-transfect along with AAV packaging vectors to produce a recombinant AAV control.

pAAV-LacZ Control Vector

AAV-402 10 µg
EUR 566
Description: Use this control vector to co-transfect along with AAV packaging vectors to produce a recombinant AAV control.

pAAV-MCS Expression Vector

VPK-410 10 µg
EUR 647
Description: Clone your gene of interest into this AAV Expression Vector, then co-transfect along with AAV packaging vectors into a packaging host cell line such as 293AAV.

pAAV-DJ/8 Vector

VPK-420-DJ-8 10 µg
EUR 647
Description: The pAAV-DJ/8 vector contains the rep and cap genes required to generated recombinant AAV of serotype DJ/8. Co-transfect with other packaging plasmids and an expression vector into 293 cells for AAV-DJ/8 packaging.

pAAV-fNPY-GFP

PVT14636 2 ug
EUR 599

pAAV- IRES- ZsGreen1

PVT11044 2 ug
EUR 301

pAAV- ZsGreen1- shRNA

PVT11045 2 ug
EUR 370

pAAV-RSV-SpCas9

PVT17629 2 ug
EUR 300

pAAV-CAG-GFP

PVT17666 2 ug
EUR 341

pAAV- MCS Plasmid

PVT2102 2 ug
EUR 241

pAAV-MCS Promoterless Expression Vector

VPK-411 10 µg
EUR 647
Description: Clone your gene of interest into this AAV Expression Vector, then co-transfect along with AAV packaging vectors into a packaging host cell line such as 293AAV.

pAAV-IRES-Puro Expression Vector

VPK-415 10 µg
EUR 647
Description: Clone your gene of interest into this AAV Expression Vector, then co-transfect along with AAV packaging vectors into a packaging host cell line such as 293AAV.

pAAV-IRES-Neo Expression Vector

VPK-416 10 µg
EUR 647
Description: Clone your gene of interest into this AAV Expression Vector, then co-transfect along with AAV packaging vectors into a packaging host cell line such as 293AAV.

pAAV-IRES-Hygro Expression Vector

VPK-417 10 µg
EUR 647
Description: Clone your gene of interest into this AAV Expression Vector, then co-transfect along with AAV packaging vectors into a packaging host cell line such as 293AAV.

pAAV-IRES-GFP Expression Vector

VPK-418 10 µg
EUR 647
Description: Clone your gene of interest into this AAV Expression Vector, then co-transfect along with AAV packaging vectors into a packaging host cell line such as 293AAV.

pAAV-IRES-Bsd Expression Vector

VPK-419 10 µg
EUR 647
Description: Clone your gene of interest into this AAV Expression Vector, then co-transfect along with AAV packaging vectors into a packaging host cell line such as 293AAV.

pAAV-EF1a-DIO-mCherry

PVT17841 2 ug
EUR 300

pAAV- IRES- hrGFP Plasmid

PVT2104 2 ug
EUR 266

Human Topoisomerase I

TG2005H-RC2 500 units
EUR 448

pAAV- CMV- mCherry- U6- sgRNA

PVT11046 2 ug
EUR 301

pAAV-hSyn-hChR2(H134R)-mCherry

PVT19026 2 ug
EUR 258

pAAV-hSyn-eNpHR 3.0-EYFP

PVT19063 2 ug
EUR 258

pAAV-EF1a-DIO-hM3D(Gq)-mCherry

PVT17847 2 ug
EUR 300

pAAV-MCS-Ppargc1a-m-FLAG-HA

PVT18341 2 ug
EUR 300

pVL1392 Vector

ABP-BVP-10001 5 ug Ask for price

pVL1393 Vector

ABP-BVP-10002 5 ug Ask for price

pORB Vector

ABP-BVP-10003 5 ug Ask for price

pAcSec1 Vector

ABP-BVP-10004 5 ug Ask for price

pAcIRES Vector

ABP-BVP-10005 5 ug Ask for price

pEE14.4 vector

PVT11901 2 ug
EUR 1036

pENTR223.1 vector

PVT11990 2 ug
EUR 352

pUB_smFLAG_KDM5B_MS2 vector

PVT11991 2 ug
EUR 352

ER2738 vector

PVT11993 2 ug
EUR 352

pFLPo vector

PVT12063 2 ug
EUR 352

pREDKI vector

PVT12064 2 ug
EUR 352

pREDCas9 vector

PVT12065 2 ug
EUR 352

PWUR790 vector

PVT12066 2 ug
EUR 352

xCas9 vector

PVT12068 2 ug
EUR 352

sgRNA vector

PVT12071 2 ug
EUR 352

PY094 vector

PVT12150 2 ug
EUR 352

PY094 vector

PVT12150-1 2 ug
EUR 352

pRGEB31 vector

PVT12152 2 ug
EUR 352

pSET152 vector

PVT3395 2 ug
EUR 376

pYLEX1 - Expression Vector

FYY203-5MG 5mg Ask for price

pYLSC1- Secretion Vector

FYY204-5MG 5mg Ask for price

pMXs Retroviral Vector

RTV-010 10 µg
EUR 624
Description: Use this construct to clone your gene for downstream recombinant retroviral packaging

pMYs Retroviral Vector

RTV-020 10 µg
EUR 624
Description: Use this construct to clone your gene for downstream recombinant retroviral packaging

pMZs Retroviral Vector

RTV-030 10 µg
EUR 624
Description: Use this construct to clone your gene for downstream recombinant retroviral packaging

pMRNAxp mRNAExpress Vector

MR000PA-1 10 ug
EUR 900

pENTR223-ATP5PO vector

PVT11685 2 ug
EUR 304

pENTR223- LC25A10 vector

PVT11686 2 ug
EUR 304

pENTR223-RSU1 vector

PVT11687 2 ug
EUR 304

pENTR223-CCDC24 vector

PVT11688 2 ug
EUR 304

pENTR223-BAT2L vector

PVT11689 2 ug
EUR 304

pENTR223-RSPH14 vector

PVT11690 2 ug
EUR 304

pENTR223-ABHD5 vector

PVT11691 2 ug
EUR 304

pENTR223-NONO vector

PVT11692 2 ug
EUR 304

pENTR223-MYOZ1 vector

PVT11693 2 ug
EUR 304

pENTR223-STX5 vector

PVT11694 2 ug
EUR 304

pENTR223-GK5 vector

PVT11695 2 ug
EUR 304

pENTR223-PIGC vector

PVT11696 2 ug
EUR 304

pENTR223-FCGR3A vector

PVT11697 2 ug
EUR 304

pENTR223-ANXA8L1 vector

PVT11698 2 ug
EUR 304

pENTR223-CDK5 vector

PVT11699 2 ug
EUR 304

pENTR223-ERP27 vector

PVT11700 2 ug
EUR 304

pENTR223-ZDHHC16 vector

PVT11701 2 ug
EUR 304

pENTR223-DFNA5 vector

PVT11702 2 ug
EUR 304

pENTR223-MPPED2 vector

PVT11703 2 ug
EUR 304

pENTR223-NIFK vector

PVT11704 2 ug
EUR 304

pENTR223-KCTD17 vector

PVT11705 2 ug
EUR 304

pENTR223-CEP170P1 vector

PVT11706 2 ug
EUR 304

pENTR223-SCML4 vector

PVT11707 2 ug
EUR 304

pENTR223-CLEC18C vector

PVT11708 2 ug
EUR 304

pENTR223-HSD17B11 vector

PVT11709 2 ug
EUR 304

pENTR223-UBXN1 vector

PVT11710 2 ug
EUR 304

pENTR223-MRPL4 vector

PVT11714 2 ug
EUR 304

pENTR223-DECR2 vector

PVT11715 2 ug
EUR 304

pENTR223-GNB3 vector

PVT11716 2 ug
EUR 304

pENTR223-FAM118B vector

PVT11717 2 ug
EUR 304

pENTR223-EIF2S2 vector

PVT11718 2 ug
EUR 304

pENTR223-HDAC11 vector

PVT11720 2 ug
EUR 304

pENTR223-RDH11 vector

PVT11721 2 ug
EUR 304

pENTR223-GNB1L vector

PVT11722 2 ug
EUR 304

pENTR223-BCL2L14 vector

PVT11723 2 ug
EUR 304

pENTR223-RPLP0 vector

PVT11724 2 ug
EUR 304

pENTR223-RALYL vector

PVT11725 2 ug
EUR 304

pENTR223-GPM6A vector

PVT11726 2 ug
EUR 304

pENTR223-BLVRA vector

PVT11727 2 ug
EUR 304

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